Elevated levels of calcium in the blood, called hypercalcemia, can sometimes be associated with certain types of cancer. However, hypercalcemia is not a sign of cancer alone and can be caused by various other factors as well.
In the context of cancer, hypercalcemia can occur for a number of reasons:
- Bone metastasis: When cancer spreads (metastasizes) to the bones, it can cause calcium to be released from the bones into the bloodstream, causing calcium levels to rise.
- Parathyroid hormone-related peptide (PTHRP): Some cancer cells produce a hormone similar to parathyroid hormone called PTHRP. This hormone can increase calcium secretion from bones and reduce calcium excretion by the kidneys, thereby contributing to hypercalcemia.
- Calcium reabsorption: Some cancers, especially those affecting the lung, breast, and multiple myeloma, can produce factors that increase calcium reabsorption in the kidney, resulting in increased calcium levels in the blood.
It is important to note that hypercalcemia can also be caused by non-cancerous conditions, such as hyperparathyroidism, kidney disease, certain medications, etc.
If you or someone you know is experiencing symptoms that may be related to hypercalcemia, such as extreme thirst, frequent urination, nausea, vomiting, abdominal pain, muscle weakness, confusion, or fatigue, seek medical attention from a medical professional. Consulting is important. They can perform appropriate tests to determine the cause of the increased calcium level and recommend appropriate treatment, if necessary. Remember that hypercalcemia can have a variety of underlying causes, and a comprehensive evaluation is needed to identify the specific cause.
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