What is alendronate sodium

Alendronate sodium is a drug that belongs to a class of drugs called bisphosphonates. It is commonly prescribed for the treatment and prevention of osteoporosis, a condition in which bones become weak and brittle and more prone to fractures. Alendronate works by inhibiting the activity of cells called osteoclasts, which are responsible for breaking down bone tissue. By reducing osteoclast activity, alendronate helps maintain bone density and strength.

What is alendronate sodium

Here are some key points about alendronate sodium:


  • Osteoporosis treatment: Alendronate is used to treat osteoporosis
    in postmenopausal women and men. It can help prevent bone fractures and increase bone density.
  • Prevention of osteoporosis: It may also be prescribed to individuals at high risk of developing osteoporosis in order to prevent the condition of osteoporosis.
  • Paget's disease: Alendronate can be used to treat Paget's disease of bone, a condition characterized by abnormal bone remodeling.


  • Alendronate sodium is usually taken as a tablet, usually once a week. It is important to follow the dosage instructions provided by your healthcare provider.

Instructions for use:

  • It is important to take alendronate on an empty stomach, usually first thing in the morning, at least 30 minutes before eating, drinking or taking any other medicines.
  • You should take alendronate with a full glass of water and stay upright (sitting or standing) for at least 30 minutes after taking the medicine, to avoid possible irritation of the esophagus.

Side effects:

  • Common side effects may include gastrointestinal symptoms such as nausea, abdominal pain and heartburn.
  • Rare but serious side effects can include irritation of the esophagus, difficulty swallowing, and more serious problems such as osteonecrosis of the jaw (a rare condition where the bone tissue of the jaw dies) or abnormal fractures of the femur.


  • It is important to inform your healthcare provider about any other medications you are taking, as some interactions may occur.
  • People with certain conditions, such as kidney problems, should use alendronate with caution.

Like any medication, it is important to consult with your healthcare provider before starting alendronate or any other medication. They can assess your medical history, order any necessary tests, and provide guidance on whether alendronate is appropriate for your specific situation.